Management of the artificial airway including secretion removal is a core skill of the respiratory therapist. The implementation of the AARC CPG has been shown to reduce complications and choice of suction catheter size remains important. Biofilm accumulation on the artificial airway is a key step in the development of pneumonia and prevention or removal is a new area of interest. As airway management continues to be a core competency of the profession, RESPIRATORY CARE receives and publishes numerous manuscripts each year on this important topic. This e-book in the Best of RESPIRATORY CARE series contains the Top 7 must-read manuscript selections related to clinical research for airway management.